Agno vs Haystack
A side-by-side comparison of capabilities, autonomy, integrations, and pricing to help you choose.
Short answer: choose Agno if you want high-performance python framework for multi-agent systems (Supervised agent, freemium); choose Haystack if you want open-source python framework for production rag, search, and agents (Supervised agent, freemium).
| Agno | Haystack | |
|---|---|---|
| What it is | High-performance Python framework for multi-agent systems | Open-source Python framework for production RAG, search, and agents |
| Type | framework | framework |
| Autonomy | Supervised agent | Supervised agent |
| Pricing | freemium | freemium |
| Best for | developers, smb, enterprise | developers, enterprise |
| Deployment | self-hosted, api | self-hosted, api |
| Modalities | text, code, api, image | text, code, api, image |
| Models | model-agnostic, open-source | model-agnostic, open-source |
| Protocols | function-calling, mcp, rest-api | function-calling, mcp, rest-api |
| Integrations | OpenAI, Anthropic, Google, Ollama, pgvector, Qdrant | OpenAI, Anthropic, Hugging Face, Ollama, Qdrant, Weaviate |
| Capabilities | 4 documented | 4 documented |
Agno
- +Strong performance focus (fast instantiation, low memory) with a clean Python API
- +Clear path from prototype to production via the AgentOS runtime
- +Broad model, vector-DB, and tool coverage, all self-hostable
- -Python-only
- -Younger and smaller ecosystem than LangChain
Haystack
- +Mature, explicit, production-oriented architecture with deep RAG and search heritage
- +Broad integrations and an Apache-2.0 license, free to self-host
- +Backed by an established vendor (deepset) with an enterprise tier
- -Python-only
- -The component and pipeline model has a learning curve versus lighter agent SDKs
Which should you choose?
Agno is high-performance python framework for multi-agent systems, best for developers, smb, enterprise. Haystack is open-source python framework for production rag, search, and agents, best for developers, enterprise. The right choice depends on the autonomy level you want, your existing integrations, and your budget, all compared above.