AutoGen vs Mastra
A side-by-side comparison of capabilities, autonomy, integrations, and pricing to help you choose.
Short answer: choose AutoGen if you want microsoft framework for multi-agent conversational ai applications (Supervised agent, free); choose Mastra if you want typescript framework for building ai agents and workflows (Supervised agent, free).
| AutoGen | Mastra | |
|---|---|---|
| What it is | Microsoft framework for multi-agent conversational AI applications | TypeScript framework for building AI agents and workflows |
| Type | framework | framework |
| Autonomy | Supervised agent | Supervised agent |
| Pricing | free · Free (open source) | free · Free (open source; pay underlying model usage) |
| Best for | developers, enterprise | developers |
| Deployment | self-hosted, api | self-hosted, api |
| Modalities | text, code, api | text, code, api |
| Models | model-agnostic, gpt, claude, open-source | model-agnostic |
| Protocols | function-calling, rest-api | mcp, function-calling, rest-api |
| Integrations | OpenAI, Azure OpenAI, Anthropic, Ollama | OpenAI, Anthropic, Google Gemini, Node.js, MCP servers |
| Capabilities | 4 documented | 3 documented |
AutoGen
- +Strong, well-known abstraction for multi-agent conversation (two-agent and group-chat patterns) from Microsoft Research
- +v0.4 rewrite brings an asynchronous, event-driven architecture with better observability and control
- +Open source, model-agnostic, and supports humans as first-class participants in agent conversations
- -Framework, not a product: autonomy and reliability depend entirely on what the developer builds
- -Now community-managed and described as in maintenance mode, with the original team's active work continuing under the renamed AG2 project
Mastra
- +TypeScript-first, filling a gap for JS/TS teams in a Python-dominated space
- +Includes agents, workflows, memory, and observability out of the box
- +Apache-2.0 licensed and backed by the experienced Gatsby team
- -TypeScript/JavaScript only
- -A framework, not a product: you build, host, and secure your agents
Which should you choose?
AutoGen is microsoft framework for multi-agent conversational ai applications, best for developers, enterprise. Mastra is typescript framework for building ai agents and workflows, best for developers. The right choice depends on the autonomy level you want, your existing integrations, and your budget, all compared above.